NR1222 has proven to be a real blessing for me, since I do not tolerate oral medications. I have had arthritis for several years, and NSAIDs were prescribed but the drugs caused stomach problems and internal bleeding A few months ago, I started using NR1222 and find that it keeps me free of pain and allows me the mobility I have not had from other products. I would recommend NR1222 to anyone, because it does the job for which it is intended…..without side effects.