My husband was diagnosed has having a form of Arthritis. He was taking between 6 and 8 Tylenol a day. I was concerned, so I bought him NR1222. He put it on as directed, and, after a week he was feeling much less pain. After 2 months he stopped taking Tylenol completely. I have recommended this product to other Arthritis sufferers. I hope they try it. It Works! Thank-you!