Before I started to use NR1222, I was in constant pain. My left leg ached from my hip to my ankle, and I had to practically drag it up steps, one step at a time. At night I had constant lower back pain which caused me to toss and turn all night trying to find a comfortable position. Since using the NR1222 cream, my leg has improved so much that I sometimes climb the stairs and feel no pain. My sleepless nights, due to back pain are over. I can truthfully say that NR1222 has improved my life greatly. I am again able to take my Granddaughter for walks, and do many things with her that I could not do before. I am going to recommend this cream to my mother who has arthritis in her hands and shoulders. I have already recommended it to a very good friend of mine who has rheumatoid arthritis and she has also had great relief from her pain is able to walk after using it. Thank you for improving my life.